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Motor instability, somnolence, and orthostatic hypotension have been reported with the use of antipsychotics, including haldol decanoate, which may lead to falls and, consequently, fractures or other fall-related injuries.
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Avoid getting up too fast from a sitting or lying positionor you may feel dizzyGet up slowly and steady yourself to prevent a fall.
Carcinogenicity studies using oral haloperidol were conducted in Wistar ratsdosed at up to 5 mg/kg daily for 24 monthsand in Albino Swiss micedosed at up to 5 mg/kg daily for 18 monthsIn the rat study survival was less than optimal in all dose groupsreducing the number of rats at risk for developing tumorsHoweveralthough a relatively greater number of rats survived to the end of the study in high-dose male and female groupsthese animals did not have a greater incidence of tumors than control animalsThereforealthough not optimalthis study does suggest the absence of a haloperidol related increase in the incidence of neoplasia in rats at doses up to 20 times the usual daily human dose for chronic or resistant patients.
HALDOL should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
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