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In a healthy volunteer crossover study n 10 , coadministration of a single 20 mg dose of simvastatin at the end of a 14-day regimen with 120 mg bid diltiazem sr resulted in a 5-fold increase in mean simvastatin auc versus simvastatin alone.

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Information about Diltiazem.

Before taking diltiazemtell your doctor if you have kidney diseaseliver diseaseor congestive heart failure.

Before you begin using a medicationbe sure to inform your doctor of any medical conditions or allergies you may haveany medications you are takingwhether you are pregnant or breast-feedingand any other significant facts about your healthThese factors may affect how you should use this medication.

Taking diltiazem could cause a slow heartbeatbradycardiawhen taken with certain heart drugsThese drugs include:

DisclaimerOur goal is to provide you with the most relevant and current informationHoweverbecause drugs affect each person differentlywe cannot guarantee that this list includes all possible dosagesThis information is not a substitute for medical adviceAlways speak with your doctor or pharmacist about dosages that are right for you.

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diltiazem may paradoxically increase ventricular rate in patients with wolff-parkinson-white syndrome because of accessory conduction pathways.