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The drug is called fludrocortisone, made by barr industries under the brand name florinef.

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Patients who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles andif exposedto obtain medical advice.

Development of hypertensionedemahypokalemiaexcessive increase in weightand increase in heart size are signs of overdosage of fludrocortisone acetateWhen these are notedadministration muestras sin coste. of the drug should be discontinuedafter which the symptoms will usually subside within several dayssubsequent treatment with fludrocortisone acetate should be with a reduced doseMuscular weakness may develop due to excessive potassium loss and can be treated by administering a potassium supplementRegular monitoring of blood pressure and serum electrolytes can help to prevent overdosagesee WARNINGS

In larger dosesfludrocortisone acetate inhibits endogenous adrenal cortical secretionthymic activityand pituitary corticotropin excretionpromotes the deposition of liver glycogenandunless protein intake is adequateinduces negative nitrogen balance.

The physiologic action of fludrocortisone acetate is similar to that of hydrocortisoneHoweverthe effects of fludrocortisone acetateparticularly on electrolyte balancebut also on carbohydrate metabolismare considerably heightened and prolongedMineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasmathey increase the urinary excretion of both potassium and hydrogen ionsThe consequence of these three primary effects together with similar actions on cation transport in other tissues appear to account for the entire spectrum of physiological activities that are characteristic of mineralocorticoidsIn small oral dosesfludrocortisone acetate produces marked sodium retention and increased urinary potassium excretionIt also causes a rise in blood pressureapparently because of these effects on electrolyte levels.

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you can buy florinef for treating conditions where the body cannot produce steroids on its own.