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HydrochlorothiazideHCTZis a diureticwater pillused for treating high blood pressurehypertensionand accumulation of fluidIt works by blocking salt and fluid reabsorption in the kidneyscausing an increased amount of urine containing saltdiuresisThe mechanism of its action in lowering high blood pressure is not well understoodThe combination of losartan and HCTZ reduces blood pressure better than either drug aloneLosartan increases potassium levels while HCTZ reduces potassium levelsthe combination of both drugs has less effect on potassium levelsThe FDA approved Hyzaar in April 1995.
Before using hydrochlorothiazide and losartantell your doctor if you have congestive heart failurekidney or liver diseaseglaucomaasthmalow or high blood levels of potassiumgoutlupusdiabetesor an allergy to sulfa drugs or penicillin.
Serious side effects have been reported with HyzaarSee theHyzaar Precautionssection.
To make sure you can safely take hydrochlorothiazide and losartantell your doctor if you have any of these other conditions:
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