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Changes in sexual desiresexual performance and sexual satisfaction often occur as manifestations of psychiatric disorders or diabetesbut they may also be a consequence of pharmacologic treatmentBecause adverse sexual reactions are presumed to be voluntarily underreportedthe Arizona Sexual Experience ScaleASEXa validated measure designed to identify sexual side effectswas used prospectively in 4 MDD placebo-controlled trialsIn these trialsas shown in Table 5 belowpatients treated with CYMBALTA experienced significantly more sexual dysfunctionas measured by the total score on the ASEXthan did patients treated with placeboGender analysis showed that this difference occurred only in malesMales treated with CYMBALTA experienced more difficulty with ability to plavix prescription assistance. reach orgasmASEX Item 4than males treated with placeboFemales did not experience more sexual dysfunction on CYMBALTA than on placebo as measured by ASEX total scoreNegative numbers signify an improvement from a baseline level of dysfunctionwhich is commonly seen in depressed patientsPhysicians should routinely inquire about possible sexual side effects.
Some medicines can interact with duloxetine and cause a serious condition called serotonin syndromeBe sure your doctor knows if you also take stimulant medicineopioid medicineherbal productsor medicine for depressionmental illnessParkinson’s diseasemigraine headachesserious infectionsor prevention of nausea and vomitingAsk your doctor before making any changes in how or when you take your medications.
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