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Close observation necessary if corticosteroids are indicated in patients with latent tuberculosis or tuberculin reactivityreactivation of the disease may occurduring prolonged corticosteroid therapythese patients should receive chemoprophylaxis.
For which conditions is this drug approvedDexamethasone is used in combination with other agents for the treatment of myeloma and lymphomasDexamethasone may also be used to help prevent or reduce nausea and vomitingto reduce swelling and related pressureor as an anti-inflammatory agentIt is important for patients to remember that physicians have the ability to prescribe medication for conditions other than those for which the drug has been approved by the FDAPatients who have received a prescription of this drug for a condition other than which it is approved may wish to discuss this issue with their physician.
Corticosteroids can produce nizoral shampoo cvs. reversible hypothalamic-pituitary-adrenalHPAaxis suppression with the potential for corticosteroid insufficiency after withdrawal of treatmentAdrenocortical insufficiency may result from too rapid withdrawal of corticosteroids and may be minimized by gradual reduction of dosageThis type of relative insufficiency may persist for months after discontinuation of therapythereforein any situation of stress occurring during that periodhormone therapy should be reinstituted.
Average and large doses of corticosteroids can cause elevation of blood pressuresodium and water retentionand increased excretion of potassiumThese effects are less likely to occur with the synthetic derivatives except when used in large dosesDietary salt restriction and potassium supplementation may be necessaryAll corticosteroids increase calcium excretion.
Steroids may increase or decrease motility and number of spermatozoa in some patients.
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