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These pharmacokinetic effects seen during cardizem coadministration can result in increased clinical effects e.

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Information about Cardizem.

Although precise mechanisms of its antianginal action are still being delineatedCARDIZEM is believed to act in the following ways:

In animal modelsdiltiazem interferes with the slow inwarddepolarizingcurrent in excitable tissueIt causes excitation-contraction uncoupling in various myocardial tissues without changes in the configuration of the action potentialDiltiazem produces relaxation of coronary vascular smooth muscle and dilation of both large and small coronary arteries at drug levels which cause little or no negative inotropic effectThe resultant increases in coronary blood flowepicardial and subendocardialoccur in ischemic and nonischemic models and are accompanied by dose-dependent decreases in systemic blood pressure and decreases in peripheral resistance.

Your doctor may occasionally change your dose to make sure you get the best results.

FDA pregnancy category CIt is not known whether diltiazem will harm an unborn babyTell your doctor if you are pregnant or viagra online reditab. plan to become pregnant while using this medication.

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