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I switched to plaquenil and laflumanide like methotrexate but you take daily which was better and less of a shock to my system its important to remember a few things every medicine reacts differently for different people.

Information about Plaquenil.
Avoid other hepatotoxicdermatotoxicQT-prolonging drugsIncreased ocular toxicity with concomitant tamoxifenMay potentiate digoxincyclosporinemonitorMay need to reduce dose of concomitant insulin or antidiabetic drugsIncreased seizure risk with other antimalarialsegmefloquineIncreased toxicity with methotrexateMay affect antiepileptics.
Blood testsIf you take this medication for a long period of timeyour doctor will likely want you to have blood tests to monitor your levels of red and white blood cells.
Kidney diseaseIf you have kidney diseaseyou may need a lower dose of this medicationTalk to your doctor about how this medication may affect your medical conditionhow the medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is needed.
Dispense in a tightlight-resistant container as defined in the USP/NFKeep out of the reach of children.
Recommended doses of the medication vary according to the condition being treated.
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