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There is practically no metabolism of the acid of latanoprost in the eyeThe main metabolism occurs in the liverThe half life in plasma is 17 minutes in manThe main metabolitesthe 1,2-dinor and 1,2,3,4-tetranor metabolitesexert no or only weak biological activity in animal studies and are excreted primarily in the urine.
Mixing eye drops containing thimerosal with latanoprost may cause precipitation of the chemicals within the dropsThereforethimerosal eye drops and latanoprost should be administered at least 5 minutes apartCombining latanoprost with other prostaglandin eye drops may reduce the effect of latanoprost and may even increase intraocular pressure.
Mixing eye drops containing thimerosal with latanoprost may cause precipitation of the chemicals within the dropsThereforethimerosal eye drops and latanoprost should be administered at least 5 minutes apartCombining no prescription prednislone for dogs. latanoprost with other prostaglandin eye drops may reduce the effect of latanoprost and may even increase intraocular pressure.
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