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There are no adequate and well-controlled studies examining sexual dysfunction with fluoxetine treatmentWhile it is difficult to know the precise risk of sexual dysfunction associated with the use of SSRIsphysicians should routinely inquire about such possible side effects.
Whether these systemic reactions and rash have a common underlying cause or are due to different etiologies or pathogenic processes is not knownFurthermorea specific underlying immunologic basis for these reactions has not been identifiedUpon the appearance of rash or of other possibly allergic phenomena for which an alternative etiology cannot be identifiedSARAFEM should be discontinued.
If concomitant use of SARAFEM with other serotonergic drugsthat istriptanstricyclic antidepressantsfentanyllithiumtramadolbuspironetryptophan and StJohn’s Wort is clinically warrantedpatients should be made aware of a potential increased risk for serotonin syndromeparticularly during treatment initiation and dose increases.
Caution is advised if the concomitant administration of fluoxetineincluding SARAFEMand other CNS acting drugs is requiredIn evaluating individual casesconsideration should be given to using lower initial doses of the concomitantly administered drugsusing conservative titration schedulesand monitoring of clinical statussee CLINICAL PHARMACOLOGY
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prozac nonexclusive name fluoxetine; brand names include flunil fontex ladose sarafem solax is one of the world s most generally endorsed antidepressants; it has been recommended for more than 40 million individuals around the world.