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Hydroxyurea is a human carcinogenIn patients receiving long-term hydroxyurea for myeloproliferative disorderssecondary leukemia has been reportedSkin cancer has also been reported in patients receiving long-term hydroxyureaAdvise protection from sun exposure and monitor for the development of secondary malignancies.
Resistant chronic myeloid leukemiaLocally advanced squamous cell carcinomas of the head and neckexcluding the lipin combination with chemoradiation.
What to do if you miss a doseTake your dose as soon as you rememberBut if you remember just a few hours before your next scheduled dosetake only one doseNever try to catch up by taking two doses at onceThis could result in dangerous side effects.
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pancreatitis, hepatotoxicity, and peripheral neuropathy have occurred when hydrea was administered concomitantly with antiretroviral drugs, including didanosine and stavudine see drug interactions .