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Information about Glucovance.
Glucovance contains a combination of glyburide and metforminGlyburide and metformin are both oral diabetes medicines that help control blood sugar levels.
Patients should be informed of the potential risks and benefits of Glucovance and alternative modes of therapyThey should also be informed about the importance of adherence to dietary instructionsa regular exercise programand regular testing of blood glucoseglycosylated hemoglobinrenal functionand hematologic parameters.
Glucovance is used together hydrocodonefrom candacheap. with diet and exercise to improve blood sugar control in adults with type 2 diabetes.
Sulfonylurea drugs are extensively bound to serum proteinsDisplacement from protein binding sites by other drugs may lead to enhanced hypoglycemic actionIn vitrothe protein binding exhibited by glyburide is predominantly non-ionicwhereas that of other sulfonylureaschlorpropamidetolbutamidetolazamideis predominantly ionicAcidic drugssuch as phenylbutazonewarfarinand salicylatesdisplace the ionic-binding sulfonylureas from serum proteins to a far greater extent than the non-ionic binding glyburideIt has not been shown that this difference in protein binding results in fewer drug-drug interactions with glyburide tablets in clinical use.
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if you need surgery, tell the surgeon ahead of time that you are using glucovance.