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While using danazolyou may need blood tests at your doctor’s officeVisit your doctor regularly.
Experience with long-term therapy with Danazol is limitedPeliosis hepatis and benign hepatic adenoma have been observed with long-term usePeliosis hepatis and hepatic adenoma may be silent until complicated by acutepotentially life-threatening intra-abdominal hemorrhageThe physician therefore should be alert to this possibilityAttempts should be made to determine the lowest dose that will provide adequate protectionIf the drug was begun at a time of exacerbation of hereditary angioneurotic edema due to traumastress or other causeperiodic attempts to decrease or withdraw therapy should be considered.
Danazol comes as a capsule to take by mouthIt usually is taken twice a day for endometriosis or fibrocystic breast diseaseor two or three times a day for hereditary angioedemaFollow the directions on your prescription label carefullyand ask your doctor or pharmacist to explain any part you do not understandTake danazol exactly as directedDo not take more or less of it or take it more often than prescribed by your doctor.
Taking danazol to treat endometriosis may increase your risk of ovarian cancerTalk with your doctor about your individual risk.
A temporary alteration of lipoproteins in the form of an increase in LDL cholesterola decrease in HDL cholesterolaffecting all subfractionsand a decrease in apolipoproteins A1 and AIIThe clinical significance of these changes is not established.
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