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Antabuse disulfiram 250 mg is contraindicated in case the patient is intolerable to the drug or its components, or exposed to alcohol in any doses, including the intake of cough syrups or other alcohol-containing medications.

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antabuse can also cause serious side effects like extreme tiredness, yellowing of skin, dark urine, seizures, and changes in appetite, severe diarrhea, vomiting, dizziness, weakness and loss of coordination.