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Bupron sr bupropion hydrochloride 150mg is a tablet that should be swallowed whole with a glass of water.
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The risk of seizure appears to be dose-relatedOther risk factors are related to patient factors e.gsevere head injuryarteriovenous malformationCNS tumor or CNS infectionor severe strokeconcomitant medications that lower the seizure thresholde.gother bupropion productsantipsychoticstricyclic antidepressantstheophyllineand systemic corticosteroidsmetabolic disordersillicit drug useabuse or misuse of prescription drugs such as CNS stimulantsdiabetes mellitus treated with oral hypoglycemics or insulintreatment with anorectic drugsand excessive use of alcoholbenzodiazepinessedative/hypnoticsor opiates.
In placebo-controlled clinical trials9and 11of patients treated with 300 and 400 mg/dayrespectivelyof the sustained-release formulation of bupropion and 4of patients treated with placebo discontinued treatment due to adverse eventsThe specific adverse events in these trials that led to discontinuation in at least 1of patients treated with either 300 mg/day or 400 mg/day of the sustained-release formulation of bupropionand at a rate at least twice the placebo rate are listed in Table 4
Allergic/anaphylactic reactions have been reported rarely with bupropionPatients should be advised to stop treatment and consult with their doctor if symptoms ariseAlthough there have been spontaneous reports of hypertension in clinical practicebupropion alone has not been associated with effects on blood pressure relative to placebo in clinical trials6364 In a clinical trial designed to look at treatment-emergent hypertensionbupropion did not differ from placebo in volunteers with preexisting untreated mild hypertension65 Howeverin a study in which bupropion was combined with a nicotine patchthere was an increased incidence of treatment-emergent hypertension in the combination group compared to the placebo group or the bupropion alone group46 Blood pressure should be monitored in patients receiving bupropion in buy nizagara in australia. combination with a nicotine patch.
You should not change your dose or stop using bupropion suddenlyunless you have a seizure while taking this medicineStopping suddenly can cause unpleasant withdrawal symptoms.
The Australian Adverse Drug Reaction Advisory Committee reported that 285 of the 780 reports it received in association with bupropion through mid-May 2001 involved psychological disturbances.
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