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Cephalosporinsincluding Supraxmay be associated with a fall in prothrombin activityThose at risk include patients with renal or hepatic impairmentor poor nutritional stateas well as patients receiving a protracted course of antimicrobial therapyand patients previously stabilized on anticoagulant therapyProthrombin time should be monitored in patients at risk and exogenous vitamin K administered as indicated.
Cefixime is a semisynthetic cephalosporin antibacterial drugsee Microbiology
Safety and effectiveness of cefixime in children aged less than six months old have not been establishedThe incidence of gastrointestinal adverse reactionsincluding diarrhea and loose stoolsin the pediatric patients receiving the suspensionwas comparable to the incidence seen in adult patients receiving tablets.
SUPRAX is indicated in the treatment of adults and pediatric patients six months of age or older with pharyngitis and tonsillitis caused by susceptible isolates of Streptococcus pyogenesNotePenicillin is the usual drug of choice in the treatment of aristocort without prescription. Streptococcus pyogenes infectionsSUPRAX is generally effective in the eradication of Streptococcus pyogenes from the nasopharynxhoweverdata establishing the efficacy of SUPRAX in the subsequent prevention of rheumatic fever is not available
Cefixime is a semisyntheticcephalosporin antibacterial for oral administrationChemicallyit is6R,7R722-Amino-4-thiazolyl)glyoxylamido8-oxo-3-vinyl-5-thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid7 2ZOcarboxy methyloximetrihydrate.
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take suprax 100 mg with food or milk if it causes stomach upset.