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The committees said in a statement that newer drugs such as crestor were not recommended because they did not meet the criteria of documented safety and cost effectiveness.
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The estimated background risk of major birth defects and miscarriage for the indicated population is unknownIn the U.Sgeneral populationthe estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4and 15-20respectively.
CRESTOR therapy should be discontinued if markedly elevated creatine kinase levels occur or myopathy is diagnosed or suspectedCRESTOR therapy should also be temporarily withheld in any patient with an acuteserious condition suggestive of myopathy or predisposing to the development of renal failure secondary to rhabdomyolysise.gsepsishypotensiondehydrationmajor surgerytraumasevere metabolicendocrineand electrolyte disordersor uncontrolled seizures
In 2010the FDA approved Crestor for prevention of heart attacksstrokes and death among fairly healthy people with elevated C-reactive proteinCRPlevels.
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