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If you develop a truly dehydrating condition like severe diarrhea, stop your metformin until you recover.

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If you experience any of the following symptomsstop taking metformin and call your doctor immediatelyextreme tirednessweaknessor discomfortnauseavomitingstomach paindecreased appetitedeep and rapid breathing or shortness of breathdizzinesslightheadednessfast or slow heartbeatflushing of the skinmuscle painor feeling coldespecially in your hands or feet.
High insulin levels can cause thickening and darkening of the skinacanthosis nigricanson the back of the neckaxillaunder the armsand groin areaIn young women with PCOShigh insulin levels can cause the ovaries to make more androgen hormones such as testosteroneThis can cause increased body hairacneand irregular or few periodsHaving insulin resistance can increase your risk of developing diabetes.
MaintenanceTitrate once/week by 500 mgno more than 2000 mg/day in divided doses.
Tell your doctor if you have recently had any of the following conditionsor if you develop them during treatmentserious infectionsevere diarrheavomitingor feveror if you drink much less fluid than usual for any reasonYou may have to stop taking metformin until you recover.
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updated 3 years ago in metformin.