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6The maximal activity of the adrenal cortex is between 2 am and 8 amand it is minimal between 4 pm and midnightExogenous corticosteroids suppress adrenocortical activity the leastwhen given at the time of maximal activityam

The information provided above on the drug you have selected is provided for your information only and is not a substitute for consultation with an appropriate medical doctorWe are providing this information solely as a courtesy andas suchit is in no way a recommendation as to the safetyefficacy or appropriateness of any particular drugregimendosing schedule for any particular cancercondition or patient nor is it in any way to be considered medical advicePatients should discuss the appropriateness of a particular drug or chemotherapy regimen with their physician.

This medication passes into breast milk but is unlikely to harm a nursing infantConsult your doctor before breast-feeding.

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What is a package insertA package insert is required by the FDA and contains a summary of the essential scientific information needed for the safe and effective use of the drug for healthcare providers and consumersA package insert typically includes information regarding specific indicationsadministration schedulesdosingside effectscontraindicationsresults from some clinical trialschemical structurepharmacokinetics and metabolism of the specific drugBy carefully reviewing the package insertyou will get the most complete and current information about how to safely use this drugIf you do not have the package insert for the drug you are usingyour pharmacist or physician may be able to provide you with a copy.

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