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Furosemide is used to clear excess fluid from your body in conditions where your body retains more than it needs.
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Pharmacodynamics Diuretic actionLoop diuretics inhibit sodium and chloride reabsorption in the proximal part of the ascending loop of Henlepromoting the excretion of sodiumwaterchlorideand potassiumAntihypertensive actionThis drug effect may be the result of renal and peripheral vasodilatation and a temporary increase in glomerular filtration rate and a decrease in peripheral vascular resistance.
Barbaro2017Dendritic cell amiloride-sensitive channels mediate sodium-induced inflammation and hypertensionCell Rep 21 1009 PMID29069584.
Treatment of edemawhich develops as a consequence of stagnation of blood circulation in heart failure as a component of complex treatment of arterial hypertension therapy for edema with chronic kidney failurenephrotic syndromeand hepatic pathologies therapy for acute kidney failure.
Allergic reactions hemoconcentration abnormal electrolyte balancedehydrationand hypovolemia increase in blood cholesterol concentrations paresthesia pressure drop orthostatic hypotensioni.ea sharp drop in blood pressure when the position of the body changes from horizontal to verticalincrease in urine dyspeptic disorderschanges in stool frequency and consistency transmitted hearing disorders due to changes in the concentration of electrolytes in the blood.
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, furosemide, bumetanide, torsemide may be particularly useful in patients with renal impairment as an alternative to thiazide diuretics or heart failure for management of fluid retention .