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It is recommended to follow a reduced calorie diet while taking xenical, and that no more than 30 of the total daily calories should come from fat sources.
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At the recommended therapeutic dose of 120 mg three times a dayorlistat inhibits dietary fat absorption by approximately 30
XENICAL may interact with concomitant drugs including cyclosporinelevothyroxinewarfarinamiodaroneantiepileptic drugsand antiretroviral drugs XENICAL can decrease cyclosporine exposureXENICAL and cyclosporine should not be simultaneously co-administered Patients should be strongly encouraged to take a multivitamin supplement that contains fat-soluble vitamins to ensure adequate nutrition because XENICAL has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene Rare cases of severe liver injury with hepatocellular necrosis or acute hepatic failure have been reportedwith some of these cases resulting in liver transplant or death Patients may develop increased levels of urinary oxalate following treatment with XENICALMonitor renal function in patients at risk for renal insufficiencySubstantial weight loss can increase the risk of cholelithiasis Exclude organic causes of obesitye.ghypothyroidismbefore prescribing XENICAL Patients should be advised to adhere to dietary guidelinesGastrointestinal events may increase when XENICAL is taken with a diet high in fat30total daily calories from fat)
Orlistat had no detectable mutagenic or genotoxic activity as determined by the Ames testa mammalian forward mutation assayV79/HPRTan in vitro clastogenesis assay in peripheral human lymphocytesan unscheduled DNA synthesis assayUDSin rat hepatocytes in cultureand an in vivo mouse micronucleus test.
Xenical is usually taken 3 times per day with each main meal that contains some fatno more than 30of flexidol. the calories for that mealYou may take the medicine either with your meal or up to 1 hour after eating.
Severe pain in your lower backblood in your urineurinating less than usual or not at alldrowsinessconfusionmood changesincreased thirstswellingweight gainfeeling short of breathsevere pain in your upper stomach spreading to your backnausea and vomitingfast heart.
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