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Consequentlyit may be useful to inform patientsor their familiesabout the signs and symptoms associated with MAOI induced hypertensive reactionsIn particularpatients should be urged to reportimmediatelyany severe headache or other atypical or unusual symptoms not previously experienced.
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Some patients given selegiline may experience an exacerbation of levodopa associated side effectspresumably due to the increased amounts of dopamine reaction with super sensitivepost-synaptic receptorsThese effects may often be mitigated by reducing the dose of levodopa/carbidopa by approximately 10 to 30
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