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FentanylOne fatal case of fentanyl intoxication due to possible fentanyl fluconazole interaction was reportedFurthermoreit was shown in healthy volunteers that fluconazole delayed the elimination of fentanyl significantlyElevated fentanyl concentration may lead to respiratory depressionPatients should be monitored closely for the potential risk of respiratory depressionDosage adjustment of fentanyl may be necessary.<\/p>\n
Use extreme caution or avoid in congenital long-QT patients and patients with conditions that increase QT-prolongation risk.<\/p>\n
Patients have rarely developed exfoliative cutaneous reactionssuch as Stevens-Johnson syndrome and toxic epidermal necrolysisduring treatment with fluconazoleAIDS patients are more prone to the development of severe cutaneous reactions to many medicinal productsIf a rashwhich is considered attributable to fluconazoledevelops in a patient treated for a superficial fungal infectionfurther therapy with this medicinal product should be discontinuedIf patients with invasive\/systemic fungal infections develop rashesthey should be monitored closely and fluconazole discontinued if bullous lesions or erythema multiforme develop.<\/p>\n
Oropharyngealesophageal candidiasisCandidiasis prophylaxis in bone marrow transplantCryptococcal meningitisCandida urinary tract infectionUTIperitonitissystemic infections.<\/p>\n
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