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A treatment regimen containing multiple immunosuppressantsincluding thiopurinesshould therefore be used with caution as this could lead to lymphoproliferative disorderssome with reported fatalitiesA combination of multiple immunosuppressantsgiven concomitantly increases the risk of Epstein-Barr virusEBVassociated lymphoproliferative disorders.<\/p>\n
Caution is necessary during the administration of Imuran to patients with hepatic dysfunctionand regular complete blood counts and liver function tests should be undertakenIn such patients the metabolism of Imuran may be impairedand the dosage of Imuran should therefore be reduced if hepatic or haematological toxicity occurs.<\/p>\n
Infection with varicella zoster virusVZVchickenpox and herpes zostermay become severe during the administration of immunosuppressantsCaution should be exercised especially with respect to the following:<\/p>\n
If you’re taking Imurancall your doctor right away if you have any of these warning signs of infection:<\/p>\n
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